Differbetween
RNA polymerase I (RNAPI) transcribes rRNA genes, RNA polymerase II (RNAPII) transcribes mRNA, miRNA, snRNA, and snoRNA genes, and RNA polymerase III (RNAPIII) transcribes tRNA and 5S rRNA genes. This is in contrast with prokaryotes where a single RNA polymerase is responsible for the transcription of all genes.
- What is the difference between RNA polymerase 1/2 and 3?
- What are the function of DNA polymerase 1/2 and 3?
- What is the role of RNA polymerase 1?
- What is the function of RNA polymerase 3?
- What does RNA polymerase II do?
- How does RNA polymerase II work?
- What's the difference between DNA polymerase 1 and 3?
- Does DNA polymerase 1 or 3 come first?
- What is 5 '- 3 exonuclease activity?
- Where is RNA polymerase III found?
- Is RNA polymerase a protein?
- How does RNA polymerase work?
What is the difference between RNA polymerase 1/2 and 3?
The main difference between RNA Polymerase 1, 2 and 3 is that the RNA polymerase 1 (Pol 1) transcribes rRNA genes and, the RNA polymerase 2 (Pol 2) mainly transcribes mRNA genes while the RNA polymerase 3 (Pol 3) mainly transcribes tRNA genes.
What are the function of DNA polymerase 1/2 and 3?
| Point of Difference | DNA Polymerase I | DNA Polymerase III |
|---|---|---|
| Type of strand synthesised | Lagging strand | Leading and lagging strands |
| Role in DNA repair | Active | No role |
| Biological functions in the cell | DNA replication, Processing of Okazaki fragments, maturation Excision repair | DNA replication, DNA repair |
What is the role of RNA polymerase 1?
RNA polymerase I transcribes the genes that encode the structural RNAs for the subunits of the ribosome. RNA polymerase II transcribes the genes that encode proteins as well as a subset of small RNAs. RNA polymerase III transcribes the genes encoding ribosomal 5S RNA, tRNAs, and a subset of other small RNAs.
What is the function of RNA polymerase 3?
In eukaryote cells, RNA polymerase III (also called Pol III) transcribes DNA to synthesize ribosomal 5S rRNA, tRNA and other small RNAs. The genes transcribed by RNA Pol III fall in the category of "housekeeping" genes whose expression is required in all cell types and most environmental conditions.
What does RNA polymerase II do?
RNA polymerase II (Pol II) is the central enzyme that catalyses DNA-directed mRNA synthesis during the transcription of protein-coding genes.
How does RNA polymerase II work?
RNA polymerase II (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA (snRNA) and microRNA. It is one of the three RNAP enzymes found in the nucleus of eukaryotic cells.
What's the difference between DNA polymerase 1 and 3?
The main difference between DNA polymerase 1 and 3 is that DNA polymerase 1 is involved in the removal of primers from the fragments and replacing the gap by relevant nucleotides whereas DNA polymerase 3 is mainly involved in the synthesis of the leading and lagging strands.
Does DNA polymerase 1 or 3 come first?
Primase synthesizes RNA primers complementary to the DNA strand. DNA polymerase III extends the primers, adding on to the 3' end, to make the bulk of the new DNA. RNA primers are removed and replaced with DNA by DNA polymerase I. The gaps between DNA fragments are sealed by DNA ligase.
What is 5 '- 3 exonuclease activity?
The 5'-3' exonuclease activity is the only active component of the N-terminus fragment of DNA Polymerase I. The main duty of the 5'-3' exonuclease activity is to remove the RNA primers at the 5' ends of newly synthesized DNA so that the polymerase activity can fill in the resulting gaps.
Where is RNA polymerase III found?
RNA polymerase III is also located in the nucleus. This polymerase transcribes a variety of structural RNAs that includes the 5S pre-rRNA, transfer pre-RNAs (pre-tRNAs), and small nuclear pre-RNAs.
Is RNA polymerase a protein?
Depending on the organism, a RNA polymerase can be a protein complex (multi-subunit RNAP) or only consist of one subunit (single-subunit RNAP, ssRNAP), each representing an independent lineage. ... RNA polymerase III synthesizes tRNAs, rRNA 5S and other small RNAs found in the nucleus and cytosol.
How does RNA polymerase work?
RNA polymerases are enzymes that transcribe DNA into RNA. ... RNA polymerase synthesizes an RNA strand complementary to a template DNA strand. It synthesizes the RNA strand in the 5' to 3' direction, while reading the template DNA strand in the 3' to 5' direction. The template DNA strand and RNA strand are antiparallel.
