Differbetween
Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian cells, while interferon beta-1b is produced in modified E. coli.
- How does interferon beta-1b work?
- What do beta interferons do?
- What class of drug is interferon beta-1a?
- Is beta interferon an immunosuppressant?
- How much does interferon beta cost?
- How is beta interferon administered?
- Does interferon cause liver damage?
- How is beta interferon made?
- What are the three types of interferons?
- What is the generic name for Avonex?
- What does interferon mean?
- Where does interferon beta come from?
How does interferon beta-1b work?
Mechanism of action
Interferon beta balances the expression of pro- and anti-inflammatory agents in the brain, and reduces the number of inflammatory cells that cross the blood brain barrier. Overall, therapy with interferon beta leads to a reduction of neuron inflammation.
What do beta interferons do?
Beta interferon (sometimes referred to as interferon beta), released at the end of an immune attack, blocks the action of gamma interferon and helps to reduce inflammation and the body's immune reaction.
What class of drug is interferon beta-1a?
Interferon beta-1a is in a class of medications called immunomodulators. It works by decreasing inflammation and preventing nerve damage that may cause symptoms of multiple sclerosis.
Is beta interferon an immunosuppressant?
Summary: Interferon proteins are normally considered virus-fighters, but scientists have found evidence that one of them, interferon beta, has an immune-suppressing effect that can help some viruses establish persistent infections.
How much does interferon beta cost?
Table 44Cost Table of RRMS Treatments
| Drug/Comparator | Strength | Annual Drug Cost ($) |
|---|---|---|
| Interferon beta-1a (Rebif) | 22 mcg (6 MIU) | $20,210 |
| Interferon beta-1a (Rebif) | 44 mcg (12 MIU) | $24,604 |
| Interferon beta-1b (Betaseron) | 0.3 mg | $20,130 |
| Interferon beta-1b (Extavia) | 0.3 mg | $18,183 |
How is beta interferon administered?
Interferon beta-1b injection comes as a powder to be mixed with liquid and injected subcutaneously (just under the skin). It is usually injected every other day. Inject interferon beta-1b injection at around the same time of day each time you inject it.
Does interferon cause liver damage?
Interferon beta is a well known cause of mild hepatic injury that occasionally can lead to severe liver injury with jaundice.
How is beta interferon made?
IFN β-1a is produced in mammalian cells (Chinese hamster ovary) using a natural human gene sequence and is glycosylated, while IFN β-1b is produced in Escherichia coli cells using a modified human gene sequence containing a genetically engineered cysteine-to-serine substitution at position 17.
What are the three types of interferons?
There are three types of interferons (IFN), alpha, beta and gamma. IFN-alpha is produced in the leukocytes infected with virus, while IFN-beta is from fibroblasts infected with virus. IFN-gamma is induced by the stimulation of sensitized lymphocytes with antigen or non-sensitized lymphocytes with mitogens.
What is the generic name for Avonex?
Generic Name: interferon beta-1a
This medication is used to treat multiple sclerosis (MS). Interferon is not a cure for MS, but it may help to slow disease worsening and decrease flare-ups of symptoms (such as balance problems, numbness, or weakness). This medication is used to treat multiple sclerosis (MS).
What does interferon mean?
Listen to pronunciation. (in-ter-FEER-on) A natural substance that helps the body's immune system fight infection and other diseases, such as cancer. Interferons are made in the body by white blood cells and other cells, but they can also be made in the laboratory to use as treatments for different diseases.
Where does interferon beta come from?
Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian cells, while interferon beta-1b is produced in modified E. coli.
