Difference Between Specificity and Selectivity

It is important to understand that the term specificity is used to tell something about the method's ability responding to one single analyte only, while selectivity is used when the method is able to respond to several different analytes in the sample.

1. What is selectivity and sensitivity?
2. What is selectivity in method validation?
3. What is selectivity in analytical chemistry?
4. What is specificity in HPLC?
5. What do you mean by selectivity?
6. What do you mean sensitivity?
7. What is selectivity of drug action?
8. How do you use specificity in method validation?
9. What is method verification?
10. What does selectivity mean in chemistry?
11. What is the selectivity of a reaction?
12. What is selectivity in organic chemistry?

What is selectivity and sensitivity?

Sensitivity refers to a radar detector's ability to pick up police signals at the greatest distance. Selectivity refers to the detector's ability to filter out signals that are not true police signals, yet operate on the same frequencies as police radar (i.e. security alarms, garage doors, automatic doors, etc.).

What is selectivity in method validation?

Selectivity of an analytical method is its ability to measure accurately an analyte in the presence of interferences that may be expected to be present in the sample matrix.

What is selectivity in analytical chemistry?

for selectivity in analytical chemistry: “Selectivity. refers to the extent to which the method can be. used to determine particular analytes in mixtures or. matrices without interferences from other. components of similar behavior.”

What is specificity in HPLC?

1. Specificity. Specificity is the ability of the analytical method to distinguish between the analyte(s) and the other components in the sample matrix [13]. In case of an HPLC method, it is assured by complete separation of peak(s) of analyte(s) from other peaks originated from the sample matrix.

What do you mean by selectivity?

The ability of the catalyst to direct the reaction to give particular products is its selectivity. For example, n-heptane in presence of platinum catalyst gives toluene.

What do you mean sensitivity?

: the quality or state of being sensitive: such as. a : the capacity of an organism or sense organ to respond to stimulation : irritability. b : the quality or state of being hypersensitive. c : the degree to which a radio receiving set responds to incoming waves.

What is selectivity of drug action?

The drugs then interact with cells or tissues where they produce their intended effects (target sites). This interaction is called selectivity. Selectivity is the degree to which a drug acts on a given site relative to other sites. Relatively nonselective drugs affect many different tissues or organs.

How do you use specificity in method validation?

Specificity refers to the ability of the analytical method to differentiate and quantify the analyte in complex mixtures. An investigation of specificity is to be conducted during the determination of impurities and validation of identification tests.

What is method verification?

Method validation and verification provides objective evidence that a method is fit for purpose, meaning that the particular requirements for a specific intended use are fulfilled. ... Method verification studies are typically less extensive than those required for method validation.

What does selectivity mean in chemistry?

Definition of Selectivity

Selectivity refers to the extent to which a method can determine particular analytes in mixtures or matrices without interferences from other components.

What is the selectivity of a reaction?

DEFINITION. The selectivity of a reaction is the ratio of the desired product formed (in moles) to the undesired product formed (in moles).

What is selectivity in organic chemistry?

Chemistry. Reactivity–selectivity principle, in general chemistry. Chemoselectivity, a term used in organic chemistry to describe reactivity of one functional group in the presence of other groups. Stereoselectivity, a term used in organic chemistry to describe the distribution of isomers in reaction products.