Differbetween
The purines in DNA are adenine and guanine, the same as in RNA. The pyrimidines in DNA are cytosine and thymine; in RNA, they are cytosine and uracil. Purines are larger than pyrimidines because they have a two-ring structure while pyrimidines only have a single ring.
- What is the difference between purines and pyrimidines quizlet?
- What is an important difference between the biosynthesis of purine nucleotides and pyrimidine nucleotides quizlet?
- Where does purine and pyrimidine synthesis occur?
- What is required for both purine and pyrimidine synthesis?
- What do purines have in common?
- What is the rule in terms of purines and pyrimidines?
- How many ATP molecules are required for the Stage 1 of the purine biosynthesis?
- Which of the following is an important precursor in purine pathway?
- What is the difference between de novo and salvage pathway of nucleotides quizlet?
What is the difference between purines and pyrimidines quizlet?
Pyrimidines have the ring built first, then the ribose (PRPP) added afterwards. Purines start with ribose and add the ring onto that.
What is an important difference between the biosynthesis of purine nucleotides and pyrimidine nucleotides quizlet?
5-phosphoribosyl 1-pyrophosphate. The synthesis of purine and pyrimidine nucleotides differ in that: purine biosynthesis starts with the formation of PRPP, whereas pyrimidines incorporate the PRPP near the end of the pathway.
Where does purine and pyrimidine synthesis occur?
Pyrimidine synthesis takes place in cytoplasm. Pyrimidine is synthesized as a free ring and then a ribose-5-phosphate is added to yield direct nucleotides, whereas, in purine synthesis, the ring is made by attaching atoms on ribose-5-phosphate.
What is required for both purine and pyrimidine synthesis?
Using 5-phosphoribosyl-1-pyrophosphate (PRPP), the de novo pathway enzymes build purine and pyrimidine nucleotides from “scratch” using simple molecules such as CO2, amino acids and tetrahydrofolate. This route of nucleotide synthesis has a high requirement for energy as compared that of the salvage pathway.
What do purines have in common?
Purines vs. Pyrimidines
| Purines | Pyrimidines | |
|---|---|---|
| Structure | Double carbon-nitrogen ring with four nitrogen atoms | Single carbon-nitrogen ring with two nitrogen atoms |
| Size | Bigger | Smaller |
| Source | Adenine and Guanine in both DNA and RNA | Cytosine in both DNA and RNA Uracil only in RNA Thymine only in DNA |
What is the rule in terms of purines and pyrimidines?
Chargaff's rules state that DNA from any species of any organism should have a 1:1 protein stoichiometry ratio (base pair rule) of purine and pyrimidine bases (i.e., A+G=T+C) and, more specifically, that the amount of guanine should be equal to cytosine and the amount of adenine should be equal to thymine.
How many ATP molecules are required for the Stage 1 of the purine biosynthesis?
Purine biosynthesis proceeds in two stages. Stage 1 requires 5 ATP molecules, with conversion of ATP-AMP counting as two equivalents of ATP in the PRPP synthetase reaction.
Which of the following is an important precursor in purine pathway?
Explanation: Glycine is an important precursor in purine pathway.
What is the difference between de novo and salvage pathway of nucleotides quizlet?
de novo synthesis: nucleotides are synthesized from simpler precursor compounds. salvage pathways: preformed bases are recovered and attached to activated riboses.
