Difference Between Filgrastim and Lenograstim

Lenograstim is obtained from Chinese hamster ovarian cells, and consists of 174 amino acids with 4% glycosylation. Filgrastim is produced using Escherichia coli, has a methionine group at its N-terminal end and is not glycosylated.

1. What is the difference between filgrastim and pegfilgrastim?
2. What is Filgrastim used for?
3. What is Filgrastim made from?
4. What is the major effect of filgrastim?
5. How much does Filgrastim cost?
6. What is the strongest chemo drug?
7. What time should filgrastim be given?
8. What are the indications for filgrastim?
9. How often should filgrastim be given?
10. Does Filgrastim increase platelets?
11. Is Filgrastim a hormone?
12. Can you drink alcohol with filgrastim?

What is the difference between filgrastim and pegfilgrastim?

Treatment regimens differ slightly: filgrastim is administered daily for up to a maximum of 14 days, either subcutaneously or intravenously, whereas pegfilgrastim treatment involves a single SC dose per chemotherapy cycle with no restrictions to every 14-day cycles only.

What is Filgrastim used for?

Filgrastim injection products (Granix, Neupogen, Nivestym, Zarxio) are used to decrease the chance of infection in people who have non myeloid cancer (cancer that does not involve the bone marrow) and are receiving chemotherapy medications that may decrease the number of neutrophils (a type of blood cell needed to ...

What is Filgrastim made from?

Filgrastim is a human granulocyte colony-stimulating factor (G-CSF)‚ produced by recombinant DNA technology.

What is the major effect of filgrastim?

Filgrastim is a growth factor that stimulates the production, maturation, and activation of neutrophils (a type of white blood cell). Filgrastim also stimulates the release of neutrophils from the bone marrow.

How much does Filgrastim cost?

Results: The cost of tbo-filgrastim treatment ranged from $312.96 (1 dose) to $4381.47 (14 doses), the cost of filgrastim-sndz treatment ranged from $351.30 to $4918.23, and the cost of filgrastim treatment ranged from $475.24 to $6653.33, compared with $4527.93 for one injection of pegfilgrastim.

What is the strongest chemo drug?

Doxorubicin (Adriamycin) is one of the most powerful chemotherapy drugs ever invented. It can kill cancer cells at every point in their life cycle, and it's used to treat a wide variety of cancers. Unfortunately, the drug can also damage heart cells, so a patient can't take it indefinitely.

What time should filgrastim be given?

How should I administer filgrastim? The injection should be given under the skin (subcutaneously) once a day, at about the same time each day: 1) To minimise any discomfort, leave the syringe you are intending to use for that day out of the fridge for 30 minutes before injecting.

What are the indications for filgrastim?

NEUPOGEN (filgrastim) is approved for 5 indications in the following patient populations:

• Chemotherapy-induced Febrile Neutropenia.
• Acute Myeloid Leukemia.
• Cancer Patients Receiving Bone Marrow Transplant.
• Peripheral Blood Progenitor Cell Collection and Engraftment.
• Severe Chronic Neutropenia.

How often should filgrastim be given?

Filgrastim is most often given as a subcutaneous injection (SQ, given under the skin), but it can be given directly into a vein (intravenous, IV). It is given once a day, preferably at the same time of day, until the neutrophil count returns to normal.

Does Filgrastim increase platelets?

Filgrastim may provide a useful option for patients with dengue who have low platelet counts. This is the first study to demonstrate that filgrastim use persistently increases the platelet and white blood cell counts within a day in patients with dengue and also reduces the duration of fever.

Is Filgrastim a hormone?

Granulocyte--colony stimulating factor (G-CSF, filgrastim) is a glycoprotein hormone of the hematopoietin family that primarily influences the proliferation and differentiation of neutrophilic granulocytic precursors.

Can you drink alcohol with filgrastim?

The drinking of alcohol (in small amounts) will not affect the safety or usefulness of filgrastim. is best to use birth control while being treated with filgrastim. Tell your doctor right away if you or your partner becomes pregnant. Do not breastfeed during treatment.