hardness of tablet

1. What is unit of hardness of tablet?
2. What is tablet hardness and tablet thickness?
3. What is the significance of determining tablet hardness?
4. How can I reduce the hardness of my tablet?
5. What is unit of hardness?
6. Why friability test is done?
7. What is a hardness test?
8. Which is most commonly used to polish the tablet?
9. Which hardness tester is most widely used?
10. How do you calculate the friability of a tablet?
11. What is disintegration test of tablets?
12. How many tablets are required for content uniformity test?

What is unit of hardness of tablet?

A tablet hardness tester is used to determine the edge-to-edge (diametral) tablet hardness. Typical hardness measurement units include: kiloponds (kp), Strong Cobb Units (SCU), and Newtons (N).

What is tablet hardness and tablet thickness?

Tablet Hardness Test. determined by the amount of tablet material and the position of the punches in relation to each other during compression. The shorter the distance between the punches, thickness, the greater the pressure applied during compression, and sometimes the harder the tablet.

What is the significance of determining tablet hardness?

These tablet hardness tests provide a meaningful picture as to the amount of force required to fracture the solid-dose tablet. This knowledge will be useful in gauging the tablet's resistance to damage that might occur during production handling, packaging, and storage.

How can I reduce the hardness of my tablet?

Most recent answer

1. Use colloidal silicon dioxide extragranularly, will give higher hardness and solve friability issue For DC Method.
2. Use slugging process For dry granulation method.
3. Use dry binder (HPC)- For DC Method.
4. Use Gelatin with starch paste will give excellent hardness For wet granulation method.

What is unit of hardness?

The SI unit of hardness is N/mm². The unit Pascal is thus used for hardness as well but hardness must not be confused with pressure. The different types of hardness discussed above have different scales of measurement.

Why friability test is done?

Friability testing is a laboratory technique used by the pharmaceutical industry to test the durability of tablets during transit. ... The result is inspected for broken tablets, and the percentage of tablet mass lost through chipping.

What is a hardness test?

The definition of hardness testing is 'a test to determine the resistance a material exhibits to permanent deformation by penetration of another harder material. ' However, hardness is not a fundamental property of a material.

Which is most commonly used to polish the tablet?

An application of wax such as carnuba wax, candelila wax, beeswax and hard paraffin is used to polish the tablets inside a polishing pan.

Which hardness tester is most widely used?

Common hardness testing types include Rockwell (indentation depth or un-recovered indentation), Knoop/Vickers, and Brinell (area of indentation). Rockwell testing is the most commonly used method by virtue of the quick results generated and is typically used on metals and alloys.

How do you calculate the friability of a tablet?

Friability is usually measured by the use of Roche fibrilator or tumbler test. A number of tablets are weighed and placed in the apparatus where they are exposed to rolling and repeated shocks as they fall 6 inches in each turn within the apparatus.

What is disintegration test of tablets?

Disintegration testing measures the ability of a tablet to break down into smaller particles or granules to allow the active drug to be absorbed into the body.

How many tablets are required for content uniformity test?

Uncoated and FilmCoated Tablets— Weigh accurately 10 tablets individually. From the result of the Assay , obtained as directed in the individual monograph, calculate the content of active ingredient in each of the 10 tablets, assuming homogeneous distribution of the active ingredient.