Synthetic

Difference Between Synthon and Synthetic Equivalent

Difference Between Synthon and Synthetic Equivalent

The key difference between synthon and synthetic equivalent is that synthon is a moiety of a chemical compound that can be formed by a known synthetic process, whereas synthetic equivalent is a reagent that carries out the function of a synthon.

  1. Which one is the correct Synthon of the synthetic equivalent?
  2. What is synthetic equivalent?
  3. What is the purpose of retrosynthetic analysis?
  4. What is a retrosynthetic analysis in organic chemistry?
  5. What is Latent polarity?
  6. What is a synthetic analysis?
  7. What is Chemoselectivity in organic chemistry?
  8. Which of the following is used as a acyl anion equivalent?
  9. What is a target molecule?
  10. What is group CX disconnection?
  11. What is group disconnection?

Which one is the correct Synthon of the synthetic equivalent?

In this case, the cyanide anion is the synthetic equivalent for the COOH synthon, while benzyl bromide is the synthetic equivalent for the benzyl synthon.

What is synthetic equivalent?

Synthetic equivalent: A reagent carrying out the function of a synthon which cannot itself be used, often because it is too unstable. • Synthon: A generalized fragment, usually an ion, produced by a disconnection. (some people also use synthon for a synthetic equivalent).

What is the purpose of retrosynthetic analysis?

Retrosynthetic analysis is a technique for solving problems in the planning of organic syntheses. This is achieved by transforming a target molecule into simpler precursor structures regardless of any potential reactivity/interaction with reagents. Each precursor material is examined using the same method.

What is a retrosynthetic analysis in organic chemistry?

Retrosynthetic analysis is a problem-solving technique for the synthesis of complex molecules. It is the art of planning organic synthesis by transforming the structure of the desired molecule to simple commercially available starting materials for its synthesis.

What is Latent polarity?

Latent Polarity:

The concept of latent polarity is an imaginary pattern of alternating (+) and (-) charges used to give an idea about the nature of synthons resulting from a disconnection of a. target molecule. The polarities are, arranged in such a way that the (+) charge is initially.

What is a synthetic analysis?

Synthetic analysis encompasses two perspectives, looking at the system on its own level and looking at it on the level of its constituents. It includes two kinds of explanations. Macroexplanations develop scientific concepts and theories for composite systems without mentioning their constituents.

What is Chemoselectivity in organic chemistry?

Chemoselectivity is a term that describes the ability of a reagent or intermediate to react with one group or atom in a molecule in preference to another group or atom present in the same molecule.

Which of the following is used as a acyl anion equivalent?

Carbanion 2, derived from 1,3-dithiane 3, is an equivalent of the acyl anion 1, which can not be generated in a synthetically useful manner.

What is a target molecule?

In medicinal chemistry, target molecules or drug targets refer to the key molecules (such as carbohydrates, proteins, and nucleic acids) that are involved in certain metabolic pathways leading to certain diseases. These target molecules are inhibited when the drug molecules bind to the active sites.

What is group CX disconnection?

Here, a bond joins the heteroatom (X) to the rest of the molecule like a C-O, C-N, or C-S group. This point is good point to initiate a disconnection. This is called a 'One-group' C-X disconnection as one would need to identify only one functional group like ester, ether, amide etc. to make the disconnection.

What is group disconnection?

Functional Group Interconversion (FGI)

Functional group interconversion is the process of converting one functional group into another during retrosynthetic analysis. FGI mostly involve oxidation, reduction, and substitution. It is applicable where we do not have real and workable reaction reverse to a disconnection.

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